NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001608
CAS NUMBER: 1309-64-4
BASE CHEMICAL NAME: ANTIMONYOXIDE
PRIMARY NAME: ANTIMONY OXIDE
CHEMICAL FORMULA: Sb2O3
STRUCTURAL FORMULA:
WLN: Not available
SYNONYMS:
DIANTIMONY TRIOXIDE
FLOWERS OF ANTIMONY
SENARMONTITE
VALENTINITE
EXITELITE
WEISSPIESSGLANZ
ANTIMONY TRIOXIDE
A1530
A1582
A1588 LP
ANTIMONIOUS OXIDE
ANTIMONY(3+) OXIDE
ANTIMONY PEROXIDE
ANTIMONY SESQUIOXIDE
ANTIMONY WHITE
ANTOX
AP 50
CHEMETRON FIRE SHIELD
CI 77052
CI PIGMENT WHITE 11
DECHLORANE A-O
NA9201
NCI-C55152
NYACOL A 1530
THERMOGUARD B
THERMOGUARD S
TIMONOX
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTIONS: White crystalline powder
MOLECULAR WEIGHT: 291.52
SPECIFIC GRAVITY: 5.67 @ 25/4 C
DENSITY: 5.2 g/mL @ 25 C
MP (DEG C): 655 C
BP (DEG C): 1550 C (sublimes); 870 C @ 210 mm Hg
SOLUBILITIES:
WATER : <1 mg/mL @ 20 C (RAD)
DMSO : <1 mg/mL @ 20 C (RAD)
95% ETHANOL : <1 mg/mL @ 20 C (RAD)
METHANOL : Not available
ACETONE : <1 mg/mL @ 20 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS:
Potassium hydroxide: Soluble
Tartaric acid: Soluble
Hydrochloric acid: Soluble
Acetic acid: Soluble
Dilute HNO3: Slightly soluble
Dilute H2SO4: Slightly soluble
VOLATILITY : Vapor pressure: 1 mm @ 574 C
FLAMMABILITY(FLASH POINT):
Flash point data for this material are not available, but it is probably
combustible. Fires involving this material can be controlled using a CO2,
foam, and/or Halon extinguishers.
UEL: Not available LEL: Not available
REACTIVITY: Not available
STABILITY: This material is stable under normal laboratory conditions.
OTHER PHYSICAL DATA:
Odorless, tasteless. Sublimes in high vacuum at 400 C.
Exists in vapor phase as Sb4O6. Heat of vaporization: 17.82 kcal/mol
Heat capacity: 24.11 cal/g/atom/C @ 21 C
Specific gravity: 5.67
TOXICITY
NIOSH REGISTRY NUMBER: CC5650000
TOXICITY:
typ. dose mode specie amount unit other
LD50 orl rat >20 g/kg
LD50 ipr rat 3250 mg/kg
LDLo ivn dog 3 mg/kg
LDLo scu rbt 2500 ug/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
Most Sb compounds are highly toxic via oral, inhal, and intraperitoneal
routes. Locally, antimony compounds are irritants to the skin and mucous
membranes.
CARCINOGENICITY:
Tumorigenic Data:
TCLo: ihl-rat 4200 ug/m3/52W-I
TC : ihl-rat 4 mg/m3/1Y-I
TD : ihl-rat 1600 ug/m3/52W-I
Review: IARC Cancer Review: Human Inadequate Evidence
IARC Cancer Review: Animal Sufficient Evidence
IARC possible human carcinogen (Group 2B) [610]
MUTATION DATA:
mrc-bcs 50 mmol/L
TERATOGENICITY:
TDLo: itt-rat 23320 ug/kg (1D male)
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: Federal Register (1/19/89) and 29 CFR 1910.1000 Subpart Z
Transitional Limit: PEL-TWA 0.5 mg/m3 [610]
Final Limit: PEL-TWA 0.5 mg/m3 [610]
ACGIH: TLV-TWA 0.5 mg/m3 [610]
NIOSH Criteria Document: Recommended Exposure Limit to this type of compounds-
air: TWA 0.5 mg(Sb)/m3 [610]
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Status: Reported in EPA TSCA Inventory, 1980
EPA TSCA Section 8(e) Status Report 8EHQ-0580-9342
Meets criteria for proposed OSHA Medical Records Rule
Standards and Regulations: DOT-Hazard: ORM-E; Label: None
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Antimony compounds, inorganic, solid, n.o.s.
UN/ID NUMBER: UN1549
HAZARD CLASS: 6.1 SUBSIDIARY RISK: None PACKING GROUP: III
LABELS REQUIRED: Keep away from food
PACKAGING: PASSENGER: PKG. INSTR.: 619, Y619 MAXIMUM QUANTITY: 100 kg, 10 kg
CARGO : PKG. INSTR.: 619 MAXIMUM QUANTITY: 200 kg
SPECIAL PROVISIONS: None
USES:
Manufacture of tartar emetic; as paint pigment; in enamels and glasses;
as mordant; in flame-proofing canvas; catalyst; intermediate; staining iron
and copper; phosphors.
COMMENTS:
Lab preparation from SbCl2 and water. Obtained from antimony ore minerals
by volatilization (roasting) process.
A second cas number, 1327-33-9, used for some of this data.
It has no RTECS material however.
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This material is toxic and a suspected carcinogen. Skin and eye contact may
prove to be irritating.
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS: Not available
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with a combination filter cartridge,
i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid
gas, SO2 and a high efficiency particulate filter).
OTHER:
Since this chemical is a known or suspected carcinogen you should contact
a physician for advice regarding the possible long term health effects and
potential recommendation for medical monitoring. Recommendations from the
physician will depend upon the specific compound, its chemical, physical and
toxicity properties, the exposure level, length of exposure, and the route
of exposure.
STORAGE PRECAUTIONS:
You should store this material in a refrigerator.
SPILLS AND LEAKAGE:
If you spill this chemical, you should dampen the solid spill material
with 5% acetic acid, then transfer the dampened material to a suitable
container. Use absorbent paper dampened with 5% acetic acid to pick up any
remaining material. Your contaminated clothing and the absorbent paper should
be sealed in a vapor-tight plastic bag for eventual disposal. Wash all
contaminated surfaces with 5% acetic acid followed by washing with a strong
soap and water solution. Do not reenter the contaminated area until the Safet
Officer (or other responsible person) has verified that the area has been
properly cleaned.
DISPOSAL AND WASTE TREATMENT:
Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a
hospital even if no symptoms (such as wheezing, coughing, shortness of breath,
or burning in the mouth, throat, or chest) develop.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Symptoms of exposure to this compound may include skin irritation and
eczema; mucous membranes inflammation; sleeplessness; fatigue; dizziness;
irritability; metallic taste; stomatitis; vomiting; diarrhea; muscular and
neuralgic pains.
SOURCES
SOURCES:
Clayton, G.D. and F.E. Clayton, Eds. Patty's Industrial Hygiene
and Toxicology. Vol. 2. Third Revised Edition. John Wiley
and Sons. New York. 1981. p. 2889-2990.
American Conference of Governmental Industrial Hygenists.
Documentation of the Threshold Limit Values. 4th ed.
American Conference of Governmental Industrial Hygenists.
Cincinnati, OH. 1980. p. 22-23.
American Conference of Governmental Industrial Hygenists.
Threshold Limit Values for Chemical Substances and
Physical Agents in the Work Environment with Intended
Changes for 1982. American Conference of Governmental
Industrial Hygenists. Cincinnati, OH. 1982. p. 10.
Weiss, G., Ed. Hazardous Chemicals Data Book. Noyes Data
Corporation. Park Ridge, NJ. 1980. p. 125.
Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Not listed.
Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1982. p. 106, #23,089-8.
Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.
Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. p. 81.
Sax, N.I. Dangerous Properties of Industrial Materials. 5th Ed.
Van Nostrand Reinhold. New York. 1979. p. 385.
Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co.
Rahway, NJ. 1983. p. 104, #736.
Weast, R.C. and M.A. Astle, Eds. CRC Handbook of Chemistry
and Physics. 63rd Ed. CRC Press, Inc. Boca Raton, FL.
1982. p. B-79, #A-274.
Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
Updates. CC5650000.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Update, p. xl; Section 3, p. 112.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. October 3, 1990.
Listed.
-------------------------------------------------------------