NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001740
CAS NUMBER: 134-62-3
BASE CHEMICAL NAME: DIETHYLTOLUAMIDE,N,N-,M-
PRIMARY NAME: N,N-DIETHYL-M-TOLUAMIDE
CHEMICAL FORMULA: C12H17NO
STRUCTURAL FORMULA: CH3C6H4CON(C2H5)2
WLN: 2N2&VR C1
SYNONYMS:
M-TOLUAMIDE, N,N-DIETHYL-
N,N-DIETHYL-3-METHYLBENZAMIDE
DIETHYL TOLUAMIDE
DIETHYL-M-TOLUAMIDE
3-METHYL-N,N-DIETHYLBENZAMIDE
M-TOLUIC ACID DIETHYLAMIDE
AI 3-22542
AUTAN
BAKER'S ANTIFOL
BENZAMIDE, N,N-DIETHYL-3-METHYL-
CHEMFORM
DEET
DELPHENE
M-DELPHENE
DET
DETA
M-DETA
DETA-20
DETAMIDE
DIELTAMID
ENT 20218
ENT 22542
M-DET
FLYPEL
METADELPHENE
MGK DIETHYLTOLUAMIDE
NAUGATUCK DET
OFF
REPEL
REPPER-DET
REPUDIN-SPECIAL
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTION: LITERATURE: Colorless or faintly yellow liquid
REPOSITORY: Clear, very faint yellow, slightly viscous
liquid
MOLECULAR WEIGHT: 191.27
SPECIFIC GRAVITY: 0.996 @ 20/4 C [029,031,047,205]
DENSITY: 0.996 g/cc @ 20 C [029,031,047,205]
MP (DEG C): -45 C (pour point) [058]
BP (DEG C): 285 C [058]
SOLUBILITIES:
WATER : <1 mg/mL @ 20 C (RAD)
DMSO : >=100 mg/mL @ 20 C (RAD)
95% ETHANOL : >=100 mg/mL @ 20 C (RAD)
METHANOL : Not available
ACETONE : >=100 mg/mL @ 20 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS:
Petroleum ether: Sparingly soluble [031,205]
Isopropanol: Miscible [172,173,295,455]
Propylene glycol: Miscible [172,173,295]
Cottonseed oil: Miscible [172,173]
Ether: Soluble [031,043,062]
Benzene: Soluble [031,062,205]
Chloroform: Miscible [295,455]
Carbon disulfide: Miscible [295]
Alcohol: Soluble [031,043,062,205]
Glycerol: Very slightly soluble [295,455]
VOLATILITY:
Vapor pressure: 1 mm Hg @ 111 C, 19 mm Hg @ 160 C [058]
Vapor density : 6.7 [058]
FLAMMABILITY(FLASH POINT):
This chemical has a flash point of 155 C (311 F) [058]. It is
combustible. Fires involving this material can be controlled with a dry
chemical, carbon dioxide or Halon extinguisher. A water spray may also be
used [058,269].
UEL: Not available LEL: Not available
REACTIVITY:
This compound is incompatible with strong acids, strong bases and
strong oxidizing agents [269]. It hydrolyzes slowly in the presence of water.
It has a solvent effect on most plastics, paints, and varnishes. It is also
incompatible with rayon, acetate or dynel clothing [058].
STABILITY:
This chemical is sensitive to prolonged exposure to moisture [058]. Sol-
utions of this chemical in water, DMSO, 95% ethanol or acetone should be sta-
ble for 24 hours under normal lab conditions (RAD).
OTHER PHYSICAL DATA:
Refractive index: 1.5212 @ 20 C [047,205]; 1.5206 @ 25 C [031,172]
Faint, pleasant odor [295]
Boiling point: 111 C @ 1 mm Hg [031,047,269]
Boiling point: 160 C @ 19 mm Hg [029,031,047,062]
Boiling point: 292 C @ 745.5 mm Hg [052]
Specific gravity: 0.996-1.002 @ 25/25 C [062]
UV max (in Cyclohexane): 274 nm (shoulder) (epsilon=600) [052]
Evaporation rate (butyl acetate=1):<1 [058]
TOXICITY
NIOSH REGISTRY NUMBER: XS3675000
TOXICITY:
typ. dose mode specie amount units other
TDLo skn hmn 35 mg/kg/5D
LDLo orl wmn 950 mg/kg
LDLo orl man 679 mg/kg
TDLo orl chd 4750 mg/kg
TDLo orl wmn 950 mg/kg
LD50 orl rat 1950 mg/kg
LC50 ihl rat 5950 mg/m3
LD50 skn rat 5000 mg/kg
LD50 orl rbt 1584 mg/kg
LD50 skn rbt 3180 mg/kg
LDLo ivn rbt 75 mg/kg
LD50 skn mus 3170 mg/kg
LD50 unr mus 1170 ug/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: Poison by intravenous route. Moderately toxic by ingestion, skin contact
and possibly other routes. Human systemic effects by skin contact:
dermatitis. An eye and skin irritant. Experimental reproductive effects
by skin contact. Mutagenic data. Can cause central nervous system
disturbances.
CARCINOGENICITY: Not available
MUTATION DATA: See RTECS printout for data
TERATOGENICITY: See RTECS printout for data
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
skn-rbt 500 mg MOD
eye-rbt 100 mg
eye-rbt 10 mg MOD
Status: EPA TSCA Chemical Inventory, 1986
EPA TSCA Test Submission (TSCATS) Data Base, September 1989
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Not restricted
UN/ID NUMBER:
HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:
LABELS REQUIRED:
PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:
SPECIAL PROVISIONS:
USES:
This compound is used as an insect repellent, as a resin solvent and in
film formers. It is also used to impregnate clothing and as a leech repellent.
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This compound is irritating to the skin, eyes and mucous membranes [031,
043]. When heated to decomposition it emits toxic fumes of carbon monoxide,
carbon dioxide and nitrogen oxides [043,058,269]. It may be harmful by inhal-
tion or ingestion [269].
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS:
GlovES+ Expert System Glove Types For The Neat (Undiluted) Chemical:
This chemical has not been tested for permeation by Radian Corporation;
however, the GlovES+ expert system was used to extrapolate permeation test
information from compounds in the same chemical class. The GlovES+ system uses
permeation data from literature sources; therefore, extra safety margins should
be used with the estimated protection time(s). If this chemical makes direct
contact with your glove, or if a tear, puncture or hole develops, replace them
at once.
The GlovES+ expert system is a tool that can help people better manage
protection from chemicals, however this tool cannot replace sound judgment nor
make technical decisions. Our GlovES+ expert system is designed to offer
initial advice and assistance in glove selection while the final glove
selection should be made by knowledgeable individuals based on the specific
circumstances involved.
Glove Type Model Number Thickness Estimated Protection Time
Viton North F-091 0.25 mm 240 min
Unknown North Silvershield 0.10 mm 480 min
PVA Edmont 25-545 0.23 mm 360 min
PE/EVAL/PE Safety4 4H 0.07 mm 240 min
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER: Not available
STORAGE PRECAUTIONS:
You should store this chemical under ambient temperatures and protect it
from moisture. Keep it away from oxidizing materials. If possible, it would
be prudent to store this compound under inert atmosphere.
SPILLS AND LEAKAGE:
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then,
use absorbent paper to pick up all liquid spill material. Your contaminated
clothing and absorbent paper should be sealed in a vapor-tight plastic bag for
eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol
followed by washing with a soap and water solution. Do not reenter the
contaminated area until the Safety Officer (or other responsible person) has
verified that the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT: Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Symptoms of exposure to this compound may include eye and mucous membrane
irritation [031,062]. It can cause contact dermatitis, conjunctivitis,
exacerbation of seborrhea and acne vulgaris [173]. Eye contact may result
in a smarting sensation [099]. Ingestion of this material can cause central
nervous system disturbances [031,043]. Symptoms resulting from exposure
to this compound include disorientation, staggering gait, slurred speech, cry-
ing out, episodes consisting of stiffening into a sitting position, extending
of extremities, flexing of the fingers and dorsiflexing the toes [151,173]. It
may also cause jaundice, aplastic anemia, bleeding, convulsive seizure or death
[173]. It may irritate tender areas of the skin [455]. It may also cause
severe eye injury [058]. Other symptoms are desquamation about the nose,
dryness of face, a slight tingling sensation and a bullous eruption in the
antecubital fossae [173]. Irritation of the gastro-intestinal tract and
coma are possible [301]. It may cause purpuric or ecchymotic areas [173].
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